Research projects

New echo parameter 4 DS Train right ventricle in correlation with genetic factors

Letter of Thanks by the Ludwig Boltzmann Institute

Expanded gene analysis and establishment of a gene bank in children with pulmonary hypertension (PH)

Effectiveness and tolerability of macitentan in the treatment of childhood pulmonary hypertension / pulmonary hypertensive vasculopathy

Long-term effects of macitentan in childhood pulmonary hypertension / pulmonary hypertensive vasculopathy

Molecular genetic examinations in pulmonary hypertension (PAH)

Interim report Molecular genetic studies in PAH and application Clinical and translational analysis of iron dyshomeostasis in patients with pulmonary arterial hypertension



Award of the René Baumgart-Stiftung foundation research prize, 2014

“Non-invasive measurement of cardiac output with a haemodynamic analyser on the basis of cardiac cycle phase analysis”

This project submitted by Prof. Irene Lang was selected in 2011. This method of measuring cardiac output would have many benefits for pulmonary hypertension patients: ease of repetition, the potential for self-measurement, the avoidance of pain and time requirement, and also the avoidance of complications.
€ 10,560.00

Support of the research project
“Continuous 7-day HHolter ECG monitoring”

The project deals with arrhythmias in cases of pulmonary hypertension, both in children/adolescents and in adults. This study is a joint project of the Clinical Cardiology Department, Internal Medicine II, and Paediatric and Adolescent Cardiology (Medical University of Vienna).
The Medical Advisory Board chose this project because this field is regarded as having been un-researched to date although the investigation of arrhythmias is important for the quality and length of life of those affected.
€ 19,685.00

„Safety and efficacy of inhaled iloprost in mechanically ventilated neonates with severe pulmonary hypertension” – Studie unter der Leitung von Univ.-Prof. Dr. Robyn J. Barst, Presbyterian Medical Center, Columbia Univ.Med.Center, New York, USA

The trial will be supported with $ 25,000.00 from the Research Association

“Electrophysiological characterisation of foetal smooth muscle cells from pulmonary arteries and ductus arteriosus – inverse O2 dependency” – study directed by Univ.-Prof. Dr. Andrea Olschewski and Univ.-Prof. Dr. Horst Olschewski at the University Hospital of Graz

The study will be supported jointly with our sponsor, Bank Austria Creditanstalt, within the framework of the initiative against pulmonary hypertension, with a sum of € 66,000.00.

Research projects in the genetics sector by Univ.-Prof. Dr. Irene Lang and Univ-Doz. Dr. Diana Bonderman, Med.Univ. Hospital Vienna, Internal Medicine II, Cardiology:

“Treprostinil for severe inoperable chronic thromboembolic pulmonary hypertension”, J Thromb Haemost 2007;5:483-9.

“Predictors of outcome in chronic thromboembolic pulmonary hypertension”, Circulation 2007;115:1-6.

“Bosentan therapy for inoperable chronic thromboembolic pulmonary hypertension”, Chest 2005;128:2599-2603.

“Medical conditions increasing the risk of chronic thromboembolic pulmonary hypertension”, Thromb Haemost 2005;93:512-6.

The studies were supported with € 50,000.00.

“Tezosentan decreases pulmonary artery pressure and improves survival rate in animal model of meconium aspiration”, R.Geiger et al. in Pediatr. Res 59:147-150, 2006, study directed by Dr. Ralf Geiger the University Hospital of Innsbruck.

The study was supported with € 25,000.00.

“VIP in pulmonary hypertension” pulmonary hypertension,
Research project directed by Dr. Ventzislav Petkov at Med.Uni. Hospital, Vienna, Pulmonology Dept. -V. Petkov, D. Dobner in J Hypertonie 2003; 7 (3):7-15

Dr. Petkov’s study supported by the Pulmonary Hypertension Research Association was recognised by the EU Commission in October 2002 and awarded funds of € 2.5 million. The city of Vienna also supported the project with € 300,000.00.



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